cancer - Pathophysiology - Genetic testing

cancer - Pathophysiology - Genetic testing
Genetic testing for high-risk individuals is already available for certain cancer-related genetic mutations. Carriers of genetic mutations that increase risk for cancer incidence can undergo enhanced surveillance, chemoprevention, or risk-reducing surgery. Early identification of inherited genetic risk for cancer, along with cancer-preventing interventions such as surgery or enhanced surveillance, can be lifesaving for high-risk individuals.

Unknown macro: {| class="wikitable"|-! Gene! Cancer types! Availability|-| BRCA1, BRCA2| Breast, ovarian, pancreatic| Commercially available for clinical specimens|- | MLH1, MSH2, MSH6, PMS1, PMS2| Colon, uterine, small bowel, stomach, urinary tract| Commercially available for clinical specimens|}

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